The action-packed NFL Week 2 is here and fans across the United States are buzzing about this weekend’s full lineup of games, key matchups, and the latest odds. Whether following the NFL Week 2 schedule, tracking the best NFL picks Week 2, or planning for Monday Night Football tonight, this guide will help navigate every angle for sports fans and survivor pools alike.
NFL Week 2 Schedule and Key Matchups
The week 2 NFL schedule kicks off on Thursday night as the Green Bay Packers host the Washington Commanders at Lambeau Field. Sunday and Monday bring a slate of marquee games, including divisional battles and early playoff previews. Here’s a look at the main national TV games and times for NFL Week 2.
2025 NFL Week 2 Full Schedule
| Day | Matchup | Time (ET) | TV |
| Thurs | Commanders @ Packers | 8:15 PM | Prime Video |
| Sun | Jaguars @ Bengals | 1:00 PM | CBS |
| Sun | Browns @ Ravens | 1:00 PM | CBS |
| Sun | 49ers @ Saints | 1:00 PM | FOX |
| Sun | Seahawks @ Steelers | 1:00 PM | CBS |
| Sun | Giants @ Cowboys | 4:25 PM | FOX |
| Sun | Eagles @ Chiefs | 4:25 PM | CBS |
| Mon | Buccaneers @ Texans | 7:00 PM | ESPN/ABC |
| Mon | Chargers @ Raiders | 10:00 PM | ESPN |
- Additional matchups include Bears @ Lions, Patriots @ Dolphins, Bills @ Jets, Rams @ Titans, Panthers @ Cardinals, Broncos @ Colts, Falcons @ Vikings.
- For ticket info, streaming options, and stadium details, check official NFL platforms.
NFL Odds Week 2: Spreads and Picks to Watch
Betting enthusiasts and survivor pools can find plenty to chew on with tight lines across the NFL odds Week 2. For example, the Cowboys (-5.5) are favored over the Giants, the Packers (-3.5) hold a Thursday night edge against the Commanders, and the Ravens (-11.5) are the week’s biggest favorites facing the Browns.
Top NFL Week 2 Odds
| Game | Spread | Over/Under | Moneyline |
| Commanders @ Packers | GB -3.5 | 48.5 | GB -192, WAS +160 |
| Giants @ Cowboys | DAL -5.5 | 44.5 | DAL -230, NYG +180 |
| Browns @ Ravens | BAL -11.5 | 45 | BAL -500, CLE +375 |
| Jaguars @ Bengals | CIN -3.5 | 49.5 | CIN -165, JAX +145 |
| Eagles @ Chiefs | PHI -1.5 | 46.5 | PHI -125, KC +105 |
| Chargers @ Raiders | LAC -3.5 | 46.5 | LAC -165, LV +145 |
| Bucs @ Texans | HOU -2.5 | 43 | HOU -140, TB +115 |
| Seahawks @ Steelers | PIT -3 | 40.5 | PIT -150, SEA +125 |
Most games have spreads under a touchdown, which means oddsmakers predict a closely contested slate in NFL week 2. For survivor contestants, pay special attention to the Ravens, 49ers, Cowboys, and Packers.
NFL Week 2 Picks & Survivor Advice
Experts are backing Dallas at home over the Giants and the Packers to cover on Thursday night. The consensus leans toward the Eagles in a Super Bowl rematch with the Chiefs, while the Steelers (-3) are a popular pick over the Seahawks due to home-field advantage.
NFL Week 2 Expert Pick Highlights
| Game | Expert Pick | Upset Watch |
| Eagles @ Chiefs | Eagles (-1.5) | Chiefs for revenge |
| Commanders @ Packers | Packers (-3.5) | Commanders on a backdoor cover |
| Giants @ Cowboys | Cowboys (-5.5) | Giants for late-game rally |
| Seahawks @ Steelers | Steelers (-3) | Seahawks as a sneaky upset |
| Patriots @ Dolphins | Patriots (+1.5) | Dolphins have offensive edge |
| Browns @ Ravens | Ravens (-11.5) | Browns to keep it closer than line |
Survivor pool players may prefer the Ravens or Cowboys this week since both teams are heavy favorites or the Packers, who have performed well on Thursday nights.
Monday Night Football Tonight: Doubleheader Action
Monday Night Football tonight features a rare doubleheader: Tampa Bay Buccaneers vs. Houston Texans at 7:00 PM ET on ABC/ESPN, followed by Los Angeles Chargers vs. Las Vegas Raiders at 10:00 PM ET on ESPN.
Fans can also stream both games via ESPN+, NFL+, or the official NFL app. Each matchup has playoff implications, making this one of the season’s most compelling Monday nights.
Week 2 NFL Schedule Table
| Date | Matchup | Time (ET) | TV |
| Sep 11 | Commanders @ Packers | 8:15 PM | Prime Video |
| Sep 14 | Jaguars @ Bengals | 1:00 PM | CBS |
| Sep 14 | Browns @ Ravens | 1:00 PM | CBS |
| Sep 14 | 49ers @ Saints | 1:00 PM | FOX |
| Sep 14 | Seahawks @ Steelers | 1:00 PM | CBS |
| Sep 14 | Giants @ Cowboys | 4:25 PM | FOX |
| Sep 14 | Eagles @ Chiefs | 4:25 PM | CBS |
| Sep 15 | Bucs @ Texans | 7:00 PM | ESPN/ABC |
| Sep 15 | Chargers @ Raiders | 10:00 PM | ESPN |
NFL Week 2 Survivor Picks: Who Stands Out?
Looking for a survivor pool pick in week 2? The top recommendations are:
- Ravens over Browns (biggest spread)
- Cowboys over Giants (elite home record)
- Packers over Commanders (Thursday night momentum)
- Eagles as a risky, high-upside play over Chiefs
Most survivor players will avoid close AFC North matchups or divisional tossups.
NFL Week 2 Player Highlights & Betting Trends
- Russell Wilson remains the Giants’ starter for another week despite early struggles.
- 15 of 16 games have spreads of 6.5 points or less, underscoring league parity this season.
- Eagles-Chiefs marks the first Super Bowl rematch since 2025, giving both squads extra motivation.
- Most anticipated rookie debut: Quarterback J.J. McCarthy for the Vikings (Week 1, but fan anticipation spills into Week 2).
FAQs
Who plays on Monday Night Football tonight?
The doubleheader features Buccaneers vs. Texans at 7:00 PM ET (ESPN/ABC) and Chargers vs. Raiders at 10:00 PM ET (ESPN).
What is the must-watch matchup in NFL Week 2?
Eagles vs. Chiefs is the game of the week—a Super Bowl rematch and a prime-time national broadcast.
Where can I find the latest NFL odds for Week 2?
NFL odds for week 2 are updated on sportsbooks and major sports sites like CBS Sports, ESPN, and FOX Sports.
What are the best survivor picks for week 2?
Survivor pool favorites include the Ravens, Cowboys, and Packers, based on spread, matchup, and home advantage.
Where can I stream NFL games in Week 2?
Games simulcast on ESPN, Prime Video, CBS, FOX, and ABC, with streaming available on ESPN+, NFL+, and the NFL app.
How many games are scheduled for NFL Week 2?
There are 16 games on the NFL Week 2 schedule, from Thursday night through doubleheader Monday night action.
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